From the late 1940s, when the island was still a British colony administered by Singapore and the Straits Settlements Administration, it was serviced occasionally by Royal Air Force (RAF) Short Sunderland flying boats before the construction of the airport in 1974. The First commercial jet service from Perth, a TAA Boeing 727, arrived on 6 June 1974. Under Australia’s two-airline policy, Ansett Airlines of Australia joined TAA on the route, providing the only direct air links with Australia. In 2024, Australia Post released a series of commemorative stamps to mark the 50th anniversary of the first flight.

Tampa affair

A brief revival of activity at the airport occurred in 2001 during the Tampa affair when the heightened Royal Australian Air Force (RAAF) traffic was complemented by a large number of Department of Immigration and Citizenship (DIAC) and media charters. During this incident, traffic at the airport is said to have been "near-continuous".

Satellite launch facility

After the closure of the casino, the resort was taken over by the Asia Pacific Space Centre, which developed plans for a satellite launch facility on Christmas Island. The company, with solid financial participation from the Australian Government, had planned to start satellite launches in 2004. Technical staff was to include 350–400 Russian rocket scientists and engineers, and componentry was to be flown in on Antonov An-124 and Boeing 747 freighters. To achieve this, the airport would need major extensions, and the Government allocated around A$55m to the task. This included a 600 m (1,969 ft) runway extension, plus additional taxiways, apron space, and other infrastructure.