Casper had airline flights in the 1930s at Wardwell Field, north of town at 42.913°N 106.35°W / 42.913; -106.35. The airport started as the Casper Army Airfield in September 1942, consisting of four asphalt hard surfaced runways – N/S, NE/SW, E/W, NW/SE – varying in length between 8,900 feet (2,700 m) and 8,600 feet (2,600 m).

Casper AAF was assigned to the Second Air Force as a heavy bomber (B-17; B-24) replacement training unit, with the 331st Bombardment Group being the training unit with four squadrons (461st, 462d, 463d and 464th Bombardment) training of personnel in heavy bomber operations. The 331st Combat Crew Training School provided ground instruction. Once personnel completed the training course, they were sent to various combat units overseas as replacement personnel.

The 331st was converted to a Very Heavy (B-29) group in July 1944 and began training for deployment to the Twentieth Air Force in the Pacific. The 211th Army Air Force Base Unit took control of the airfield. Casper AAF became part of the Air Transport Command as a transit station for WASP pilots ferrying combat aircraft across the United States. The airfield was inactivated in March 1945, and on 30 September 1945 was turned over to the Army Corps of Engineers as surplus.

The War Assets Administration turned the airfield over to civil control in the late 1940s, and in 1949 it became Natrona County Municipal Airport, replacing the former Casper Airport, Wardwell Field, whose runways are now streets in the town of Bar Nunn.